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| Date | Type | Move |
|---|---|---|
| 2026-09-28 | Waiver claim | St. Louis Cardinals claimed RHP Chase Hampton off waivers from Washington Nationals. |
| 2026-09-18 | Outright | St. Louis Cardinals sent RHP Peter Strzelecki outright to Memphis Redbirds. |
| 2026-09-16 | DFA | St. Louis Cardinals designated 3B Ramón Urías for assignment. |
| 2026-09-16 | DFA | St. Louis Cardinals designated RHP Peter Strzelecki for assignment. |
| 2026-08-29 | DFA | St. Louis Cardinals designated LHP Caleb Ferguson for assignment. |
| 2026-08-10 | Waiver claim | Houston Astros claimed LF Nelson Velázquez off waivers from St. Louis Cardinals. |
| 2026-08-08 | DFA | St. Louis Cardinals designated LF Nelson Velázquez for assignment. |
| 2026-08-06 | Waiver claim | St. Louis Cardinals claimed RF Everson Pereira off waivers from Chicago White Sox. |
| 2026-08-06 | Outright | St. Louis Cardinals sent RHP Tink Hence outright to FCL Cardinals. |
| 2026-08-01 | DFA | St. Louis Cardinals designated RHP Tink Hence for assignment. |
| 2026-07-23 | Waiver claim | Baltimore Orioles claimed C Yohel Pozo off waivers from St. Louis Cardinals. |
| 2026-07-22 | DFA | St. Louis Cardinals designated RHP Scott Blewett for assignment. |
| 2026-07-17 | DFA | St. Louis Cardinals designated C Yohel Pozo for assignment. |
| 2026-07-12 | Outright | St. Louis Cardinals sent LHP Bruce Zimmermann outright to Memphis Redbirds. |
| 2026-07-10 | Outright | St. Louis Cardinals sent LHP Jared Shuster outright to Memphis Redbirds. |
| 2026-07-08 | DFA | St. Louis Cardinals designated LHP Bruce Zimmermann for assignment. |
| 2026-07-08 | DFA | St. Louis Cardinals designated LHP Jared Shuster for assignment. |
| 2026-06-18 | DFA | St. Louis Cardinals designated RHP Chris Roycroft for assignment. |
| 2026-05-31 | DFA | St. Louis Cardinals designated RHP Matt Pushard for assignment. |
| 2026-05-18 | Outright | St. Louis Cardinals sent LHP Jared Shuster outright to Memphis Redbirds. |
| 2026-05-16 | DFA | St. Louis Cardinals designated LHP Jared Shuster for assignment. |
| 2026-05-03 | Waiver claim | Chicago Cubs claimed LHP Luis Peralta off waivers from St. Louis Cardinals. |
| 2026-05-01 | DFA | St. Louis Cardinals designated LHP Luis Peralta for assignment. |
| 2026-04-27 | Waiver claim | St. Louis Cardinals claimed LHP Luis Peralta off waivers from Colorado Rockies. |
| 2026-04-16 | Outright | St. Louis Cardinals sent LHP Jared Shuster outright to Memphis Redbirds. |
| 2026-04-13 | DFA | St. Louis Cardinals designated LHP Jared Shuster for assignment. |
| 2026-04-05 | DFA | St. Louis Cardinals designated LHP Nick Raquet for assignment. |
| 2026-02-26 | Waiver claim | Minnesota Twins claimed RHP Zak Kent off waivers from St. Louis Cardinals. |
| 2026-02-21 | DFA | St. Louis Cardinals designated RHP Zak Kent for assignment. |
| 2026-02-20 | Waiver claim | Baltimore Orioles claimed 3B Bryan Ramos off waivers from St. Louis Cardinals. |
| 2026-02-16 | DFA | St. Louis Cardinals designated 3B Bryan Ramos for assignment. |
| 2026-02-16 | Waiver claim | St. Louis Cardinals claimed RHP Zak Kent off waivers from Texas Rangers. |
| 2026-02-06 | Waiver claim | St. Louis Cardinals claimed 3B Bryan Ramos off waivers from Baltimore Orioles. |
| 2026-01-09 | Waiver claim | Texas Rangers claimed RHP Zak Kent off waivers from St. Louis Cardinals. |
| 2026-01-06 | DFA | St. Louis Cardinals designated RHP Zak Kent for assignment. |
Waiver rows: the official MLB StatsAPI transaction feed's waiver-claim, designated-for-assignment and outright-assignment entries involving the club on either side, 2026 season to date. Free-agency elections that follow a DFA are a different feed type and stay on the transaction log. Every trade, signing and release involving the Cardinals is also staged: see the 2026 Cardinals transaction log or the full 1945-2026 transaction archive.